According to the World Health Organisation, hepatocellular carcinoma (HCC) is the 5th most common cancer in men and 9th most common cancer in women worldwide. It is also the 2nd most common cause of cancer-related death. HCC accounts for about 80% of primary liver cancers.
The incidence of liver cancer is highest in eastern and south-eastern Asia. In Singapore, it is the 4th most common cancer in males with approximately 24.8 cases per 100,000 cancer cases.